Recombinant human Utrophin   

DHTX; Disrupted in heterotaxy; p63; UV radiation resistance associated; UV radiation resistance associated gene; UV radiation resistance associated gene protein; UV radiation resistance-associated gene protein; Utrophin; Utrophin_HUMAN.    

濃度：1mg/ ml

來源：Recombinant Human

純度：≥95% SDS-PAGE

表達系統(tǒng)：Wheat germ

標簽：GST tag N-Terminus

蛋白長度：Protein fragment

內毒素水平：<1.000 Eu/µg

純化方法：HPLC

應用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保質期：1年

Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.

抗體

產(chǎn)品名稱：Rabbit Anti-Utrophin antibody

Rabbit Anti-Utrophin  

別名：DMDL; DRP 1; DRP; DRP-1; DRP1; Dystrophin like protein; Dystrophin related protein 1; Dystrophin related protein; Dystrophin-related protein 1; FLJ23678; UTRN; UTRO_HUMAN; Utrophin (homologous to dystrophin); Utrophin     

來源：Rabbit

克隆類型：Polyclonal

濃度：1mg/ml

亞型：IgG

應用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應：Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog)

理論分子量：394kDa

免疫原：KLH conjugated synthetic peptide derived from Human Utrophin 

保存：-20℃
保質期：1年

單克隆抗體

產(chǎn)品名稱：Anti-Utrophin antibody

Mouse Anti-Utrophin 

別名：DMDL; DRP 1; DRP; DRP-1; DRP1; Dystrophin like protein; Dystrophin related protein 1; Dystrophin related protein; Dystrophin-related protein 1; FLJ23678; UTRN; UTRO_HUMAN; Utrophin (homologous to dystrophin); Utrophin  

來源：Mouse

克隆類型：Monoclonal

濃度：1mg/ml

亞型：IgG

應用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應: Human 

理論分子量：394kDa

免疫原：KLH conjugated synthetic peptide derived from Human Utrophin  

保存：-20℃
保質期：1年

Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.